Glucosamine is a natural amino monosaccharide and a precursor of mucopolysaccharides, which are the main components of articular cartilage. Therefore, glucosamine is a nutrient that promotes the formation of chondrocytes and is also a natural component of healthy articular cartilage. The common glucosamine chondroitin on the market is composed of two nutrients: glucosamine and chondroitin sulfate.
Glucosamine is a compound in which one hydroxyl group of glucose is replaced by an amino group. It was first isolated from the hydrolysis product of chitin by German surgeon and pharmacist Georg in 1876. Glucosamine is essential for the biosynthesis of glycosaminoglycans (GAG). GAG is an important substance used in animals to bind water to form a buffer, lubricate and protect hyaline cartilage.
Glucosamine hydrochloride is a natural compound widely present in human articular cartilage and is mainly used in the field of health care products. The application of glucosamine hydrochloride in health care foods is mainly focused on promoting bone health. With age, the body's ability to synthesize glucosamine will gradually decline, resulting in affected articular cartilage metabolism, which may cause bone and joint discomfort or related diseases. Supplementation of glucosamine hydrochloride can help regulate body functions, promote the synthesis of proteoglycans in cartilage tissue, maintain the normal structure of articular cartilage, increase osteoblast differentiation, accelerate bone calcium deposition, improve osteoporosis, and has anti-inflammatory effects.
As an important health food raw material, glucosamine hydrochloride is widely used in various joint health products. Such as glucosamine chondroitin calcium tablets, glucosamine capsules, etc. These products can help people prevent and relieve joint diseases and maintain joint health. It can be used in combination with other nutrients such as collagen and chondroitin sulfate to improve the efficacy of the product. It is also used in cosmetics, with moisturizing and anti-oxidation effects.
Glucosamine itself is a substance that exists in the human body. It has a history of safe use for many years, with a low incidence of adverse reactions and good safety.
Manufacturers usually conduct strict quality control on glucosamine hydrochloride to ensure its purity and potency. The product inspection report shows high content, low drying loss, qualified specific rotation, and heavy metal and microbial counts are controlled within a safe range.
Glucosamine sulfur is a natural component of joint cartilage tissue. It can help repair and nourish cartilage and prevent the occurrence of joint diseases.
ITEMS |
STANDARDS |
RESULTS |
Product Name |
Glucosamine Hydrochloride |
/ |
Appearance |
White or off white crystalline powder |
Complies |
Mesh Size |
90% pass 80 mesh |
Complies |
Identification |
A:IR conforms to reference standard. |
Complies
|
Identification |
B:Meets the requirements of the tests for chloride |
|
Identification |
C:The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay |
|
Assay |
98.00%- 102.00% |
99.46% |
SpecificRotation(25℃) |
+70。- +73。 |
+71.2° |
Chloride |
16.2%~16.7% |
16.5% |
pH (2%,25°) |
3.0-5.0 |
4.4 |
Loss on drying |
<1.00% |
0.029% |
Residue on Ignition |
<0. 1% |
0.05% |
Heavy Metals(ppm) |
<10 |
<10 |
Lrouic(ppm) |
<10 |
<10 |
Arsenic(ppm) |
<0.5 |
<0.5 |
Lead(ppm) |
<0.5 |
<0.5 |
Sulfate |
<0.24 |
Complies |
Total plate count |
<1000CFU/g (USP2021) |
Complies |
E-coli and Salmonella |
Negative |
Negative |
Packing: |
25kg /drum |
|
Conclusion: |
The product was inspected according to Conform to theUSP42 standard and customer requirements, and the results were in line with the regulations and judged to be qualified. |
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