Coenzyme Q10, NMN, PQQ: Scientific Comparison of the Three Major Coenzymes

Time : 2025.03.14 Page View : 483 Author : Alice

What is PQQ?

PQQ (pyrroloquinoline quinone) is a coenzyme of oxidoreductase. Its unique o-benzoquinone structure gives it many different physiological properties from other coenzymes, and also gives it different physiological effects. PQQ is a very effective antioxidant and plays an important role in brain cognition and memory. Since the human body cannot synthesize PQQ on its own, it usually needs to be supplemented through dietary supplements, which are mostly in powder form and prepared by microbial fermentation.

What is NMN?

NMN, the full name of β-nicotinamide mononucleotide, is nucleotide diphosphate, a precursor of vitamin B3 that can be converted into NAD+ in cells. NAD+ is an intracellular energy molecule that can affect many basic functions of the body, including mitochondrial function, DNA repair and cell regeneration. As we age, the level of NAD+ in the body decreases, which is closely related to aging and the occurrence of various diseases. Therefore, supplementing NMN is believed to help increase NAD+ levels, thereby improving cell function and delaying the aging process.

What is Coenzyme Q10?

Coenzyme Q10 is a fat-soluble small molecule compound that is mainly present on the inner membrane of mitochondria. It participates in the process of oxidative phosphorylation and is a key component of cellular energy metabolism. It is also a powerful antioxidant that can scavenge free radicals and protect cells from oxidative stress damage. With age, the synthesis capacity of Coenzyme Q10 gradually decreases, resulting in impaired cellular energy metabolism and increased oxidative stress. Therefore, supplementing Coenzyme Q10 helps to improve cellular energy levels, enhance antioxidant capacity and delay cell aging.

Difference between PQQ and Coenzyme Q10

PQQ (pyrroloquinoline quinone) and Coenzyme Q10 are both bioactive substances with antioxidant and anti-inflammatory effects, but they differ in structure, function and application. PQQ is a compound that can promote the generation of new mitochondria in cells and improve the efficiency of energy production. It helps to improve skin quality and slow down aging. It has a strong antioxidant capacity, which is 7.4 times that of vitamin C, and has stronger thermal stability. It is defined as a new type of B vitamin and has obtained health certification in many countries. It is often used in combination with raw materials such as NMN, mainly for brain health, sleep aid and oral beauty. Coenzyme Q10 is mainly used for the treatment and prevention of cardiovascular and cerebrovascular diseases, promoting heart health and increasing energy.

Currently, the common PQQ supplement products on the market are mainly aimed at brain health, sleep aid, oral beauty, etc., and are often used in combination with various raw materials such as MNM and coenzyme Q10.

The role of PQQ, NMN and coenzyme Q10

When PQQ, NMN and coenzyme Q10 are used together, they can synergistically enhance immunity, promote cell regeneration and repair, and delay aging. PQQ and NMN can work together to increase NAD+ levels and enhance cell metabolism, especially in preventing aging and liver health. The combination of coenzyme Q10 and PQQ can enhance cardiovascular function and oxidoreductase activity and prevent lipid peroxidation. PQQ can also improve the absorption and bioavailability of NMN, so the two are often used together to achieve better health effects. Overall, the combined supplementation of these three substances helps maintain the normal physiological functions of the body and improve the overall health level.

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